Publications

Our latest preprint:

Meza-Resillas J, O’Hara F, Kaushik S, Stobart MJ, Ahmadpour N, Kantroo M, Shabanipour S, Del Rosario J, Rodriguez M, Koval D, Glück C, Weber B, Stobart JL. (2024). L-Type calcium channels and TRPC3 channels shape brain pericyte calcium signaling and hemodynamics throughout the arteriole to capillary network in vivo. bioXriv: doi: https://doi.org/10.1101/2024.02.27.582351

Selected publications:

• Ahmadpour N*, Kantroo M*, Stobart MJ, Meza-Resillas J, Shabanipour S, Parra-Nuñez J, Muzaleva A, Salamovska T, O’Hara F, Erickson D, Di Gaetano B, Carrion-Falgarona S, Weber B, Lamont A, Lavine N, Kauppinen T, Jackson MF, Stobart JL. (2024). Cortical astrocyte N-methyl-D-aspartate receptors influence whisker barrel activity and sensory discrimination in mice. Nature Communications. 15:1571.

• Tsai YC, Hleihil M, Otomo K, Abegg A, Cavaccini A, Panzanelli P, Cramer T, Ferrari KD, Barrett M, Bosshard G, Karayannis T, Weber B, Tyagarajan SK *, Stobart JL *. (2024). The gephyrin scaffold modulates cortical layer 2/3 pyramidal neuron responsiveness to single whisker stimulation. Scientific Reports. 14:4169.

• Stobart JL, Erlebach E, Glueck G, Barrett MJP, Li M, Vinogradov SA, Klohs J, Zarb Y, Keller A, Weber B. (2022). Altered hemodynamics and vascular reactivity in a mouse model with severe pericyte deficiency. Journal of Cerebral Blood Flow and Metabolism.

• Meza-Resillas J*, Ahmadpour N*, Stobart M, Stobart J. (2021). Brain mural cell calcium and hemodynamic imaging in transgenic mice in vivo. Journal of Visualized Experiments. DOI: 10.3791/62725-v 

• Ahmadpour N, Kantroo M, Stobart J. (2021). Extracellular calcium influx pathways in astrocyte calcium microdomain physiology. Biomolecules. 11(10): 1467.

• Zhang K, Förster R, He W, Liao X, Li J, Yang C, Qin H, Wang M, Ding R, Li R, Jian T, Wang Y, Zhang J, Yang Z, Jin W, Zhang Y, Qin S, Lu Y, Chen T, Stobart J, Weber B, Adelsberger H, Konnerth A, Chen X. (2021). Fear learning induces alpha7-nicotinic acetylcholine receptor-mediated astrocytic responsiveness that is required for memory persistence. Nature Neuroscience. 24(12): 1686-1698.

• Glueck C, Ferrari KD, Keller A, Saab A, Stobart J, Weber B. (2021). Cortical capillary pericytes sense neuronal activity via potassium. eLife. 10:e70591.

• Arizono M, Panatier A, Krishna Inavalli VGG, Pfeiffer T, Angibaud J, Stobart J, Bellocchio L, Marsicano G, Mikoshiba K, Oliet SHR, Weber B, Nägerl UV. Structural basis of astrocytic Ca2+ signals at tripartite synapses. 2020. Nature Communications. 11(1): 2541

• Zuend M, Saab AS, Wyss MT, Ferrari KD, Stobart J, Barros FL, Weber B. Arousal-induced cortical activity triggers lactate release from astrocytes. 2020. Nature Metabolism. 2, 179-191.

• Baeza-Lehnert F, Saab A, Gutiérrez R, Larenas V, Díaz E, Horn M, Hösli L, Stobart J, Hirrlinger J, Weber B, Barros LF. Non-canonical control of neuronal energy status by the Na+ pump. 2019. Cell Metabolism. 29(3):668-680.e4.

• Stobart JL, Ferrari KD, Barrett MJP, Glueck C, Stobart MJ, Zuend M, Weber B. (2018). Cortical circuit activity evokes rapid astrocyte calcium signals on a similar time scale to neurons. Neuron. 98(4): 726-735.

• Stobart JL* , Ferrari KD*, Barrett MJP, Stobart MJ, Looser ZJ, Saab AS, Weber B. (2018). Long-term in vivo calcium imaging of astrocytes reveals distinct cellular compartment responses to sensory stimulation. Cerebral Cortex. 28: 184-198.

• Barrett MJP, Ferrari KD, Stobart JL, Holub M, Weber B. (2018). CHIPS: an extensible toolbox for cellular and hemodynamic two-photon image analysis. Neuroinformatics. 16(1): 145-147.

• Schlegel F, Sych Y, Schröter A, Stobart J, Weber B, Helmchen F, Rudin M. (2018). Fiber-optic implant for simultaneous fluorescence-based calcium recordings and BOLD fMRI in mice. Nature Protocols. 13(5): 840-855.

• Mächler P, Wyss MT, Elsayed M, Stobart J, Gutierrez R, von Faber-Castell A, Kaelin V, Zuend M, San Martín A, Romero-Gómez I, Baeza-Lehnert F, Lengacher S, Schneider BL, Aebischer P, Magistretti PJ, Barros LF, Weber B. (2016). In vivo evidence for a lactate gradient from astrocytes to neurons. Cell Metabolism. 23(1): 94-102.

• Stobart JL, Anderson CM. (2013). Multifunctional role of astrocytes as gatekeepers of neuronal energy supply. Frontiers in Cellular Neuroscience. 7(38): 1-21.

• LeMaistre Stobart JL* , Lu L* , Anderson HD , Mori H , Anderson CM. (2013). Astrocyte-induced cortical vasodilation is mediated by D-serine and endothelial nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. 110(8): 3149-54.